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Symbol
Name
ID

Lig4
ligase IV, DNA, ATP-dependent
MGI:1335098

Phenotype annotations related to digestive/alimentary system

Darker colors indicate more annotations

Human Phenotypes	Hereditary nonpolyposis colorectal carcinoma	Colon cancer	Intestinal pseudo-obstruction	Neoplasm of the stomach	Intermittent diarrhea	Nausea and vomiting	Functional abnormality of the gastrointestinal tract	Functional intestinal obstruction	Neoplasm of the liver
Disease(s) Associated with LIG4	Hereditary nonpolyposis colorectal carcinoma	Colon cancer	Intestinal pseudo-obstruction	Neoplasm of the stomach	Intermittent diarrhea	Nausea and vomiting	Functional abnormality of the gastrointestinal tract	Functional intestinal obstruction	Neoplasm of the liver
colorectal cancer
multiple myeloma
pancreatic cancer

Mouse Phenotypes		increased colon adenocarcinoma incidence	intestinal inflammation
Availability	Mouse Genotype
	Lig4^tm2.1Fwa/Lig4^tm2.1Fwa

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23